She is the granddaughter of the North Wolf Demon Tribe's leader. Later, upon knowing that Naraku was the one who tricked her and Inuyasha to hate each other, Kikyo set her goal to destroy him by allowing the evil man to complete the Shikon Jewel; fragment by fragment and then purify him along with it. Ginkotsu's jewel shard is subsequently used by Renkotsu to heal his wounds. Oh, we wouldn't want that, would we, Inuyasha? At first she is motivated solely by the desire to free her brother from Naraku's influence, but overtime she develops mutual affection and loyalty for the entire group.
Bankotsu was overjoyed by this, saying that Jakotsu was such a good friend, and the only person he can trust.
Both the demon and Midoriko died, but their souls combined to give birth to the Shikon Jewel. Because of this, Hojo is frequently seen giving Kagome traditional remedies and supplies for her various fictional illnesses. In the anime, she loses her eye while helping defend the village from a demon attack shortly before the Shikon Jewel incident. Jakotsu instantly recognized him as the one that killed Mukotsu.
As Byakuya was designed to only exist as long as Naraku lives, his body can be severely damaged when Naraku suffers mortal injuries.